月度归档 2025年4月19日

Interview | After 90, he shot the acting peak of the Golden Rooster Award for Best Actress.

The pilot poster was created by Luo Xi, who graduated from Russian Repin Academy of Fine Arts, and director Li Xu.


Special feature of 1905 film network Li Xu, a teacher of Beijing Film Academy and post-90s director, directed his first feature film Sunflower in the Evening.


Screenwriters Liu Yibing and production designer, photography director Jin Guirong, modeling director, editing director, sound director Liu Xiaofei, composer Guo Haowei, etc. These names may be a little strange to ordinary movie audiences, but as long as you know a little about the history of contemporary movies in China, you must understand the heaviness of such a lineup.


The heroine of the film is the best actress who won both the Golden Rooster Award and the China Watch Award. These names are put together, and it is not an exaggeration to describe them as "palace level".Open the resumes of the masters, including a large number of classic works such as Latency.


What kind of movie will Sunflower in the Evening be when the post-90s new director meets the Golden Rooster and China Watch double-prize winner and the academic lineup?The film was previously shown as a special recommendation for the opening of the "Southern China (Zhuhai) Film Week" of the 30th University Student Film Festival of Beijing International Film Festival, and it is planned to be shown nationwide this year.


Director Li Xu once mentioned that as a movie fan, he was immersed in the film world of alexandro jodorowsky and other directors, and he also knew a lot about this kind of works.


What kind of style will it be when he picks up the guide tube and makes a movie himself? In 1905, the film network interviewed Li Xu, the director, and unveiled the mystery of Sunflower in the Evening in advance.


Director Li Xu.


01

A movie without a "story"


What kind of story will happen to a woman who has to face illness and death?Sunflower in the Evening tells the story of Xu Manfang, an urban woman, who decided to give up treatment and return to the place where she was young after suffering from a terminal illness, where she made new friends and regained memories of youth, and spent the last part of her life.


Li Xu, the director, said frankly that he wanted to think about life philosophy issues about life and death. "When knowing that life is about to press the stop button, Xu Manfang’s mood is different from ours, and her inner confusion and fear are very strange. This strangeness provides a different perspective for the film in terms of technique and form."


"I want to write a movie without any external plot conflict", Li Xu insisted on making an inward exploration work. During the script creation stage, he deduced many versions, but he was never satisfied. Finally, with the help of teacher Liu Yibing, the story content has both an abstract core and a concrete mystery.



The first draft of the script was originally named "Weird Woman", but Li Xu felt too straightforward. At that time, he happened to turn to a song list he had created before, called "Sunflower in the Evening", which was just in line with the temperament that the film wanted to pursue — — Sunflowers in the evening are still born in the sun, and there is a great romantic optimism.


Li Xu said, "This film will provide the audience with infinite possibilities of reading. It is a summoning structure, that is, it gives you a bowl, and you put all your life experiences and experiences into it to turn it into a complete and full work. It means that we have done a comma, and the final period should be given to the audience. "


02

Renhua Na: This may be my acting peak.


Renhua Na, the heroine, said to Li Xu after watching the film, "This may be the peak of my acting in my life.". This heartfelt feeling is a great affirmation for Li Xu.


Before the cooperation, Renhua Na had other new film invitations in the same period. It was the script of Sunflower in the Evening and the experimental and exploratory shooting techniques that attracted her to choose to star in this film. After filming, Renhua Na told Li Xu that her name means "sunflower" in Mongolian, and she was destined to have a deep fate with this film.


Renhua Na starred in Sunflower in the Evening.


Renhua Na’s acting skills have always been well-known. She has been nominated for the "Three Golden Awards" in China films for films such as "The Rustling of the Hunan Daughter", and won the Golden Rooster Award for Best Actress and the Chinese Film China Watch Award for Excellent Actress for her "Eji".


Renhua Na is very good at portraying people who are calm in appearance and complicated in heart, and Xu Manfang is also such a role. During the filming process, Li Xu hoped that Renhua Na could follow Xu Manfang into the mountain village alone, and in the process of life, he showed a state from not having a "soul" to gradually forming a "soul", so as to shape the whole role.


"Her performance is extremely flexible, with a particularly calm side and a particularly strong impact." Li Xu thinks that Renhua Na’s performance is completely beyond his original imagination, which endows the role with greater charm.


03

Professor-level academic school behind-the-scenes big coffee to create


"It is both lucky and difficult to connect this film with so many big coffees." During the creation, Li Xu fully felt the aesthetic height and instinct of the senior behind-the-scenes predecessors of the academic school, and their innovative designs and ideas made the film have a more advanced audio-visual aesthetics.



Juiping Cao, a professor from production designer and China Communication University, has cooperated with the director for many times and participated in the art work of classic works such as Hanging the Red Lantern High, story of qiu ju and My Father and Mother.


At an expert seminar on the film Sunflower in the Evening held not long ago, Mr. Juiping Cao once told reporters that he and Director Li Xu had found the artistic tone for the whole film by referring to the painting style of Danish painter Wilhelm Hammerhuy.


Li Xu University majored in film and television and photography, and now teaches the basic course of photography modeling at Beijing Film Academy. This film also reflects his thinking of telling stories with images.


Together with Jin Guirong, director of photography and professor of Communication University of China, he decided to adopt the form of single-camera long lens shooting, striving for perfection in composition, mirror movement and light and shadow, and at the same time using visual modeling images such as sunflower, shadow play and mirror, trying to construct poetic image characteristics for the film.


Director Li Xu is at the shooting scene of the movie Sunflower in the Evening.


The post-editing work of the film is also a "hundred turns and thousands of times" honing process, and the editing of every plot content is repeatedly "turned over" in the mind of director Li Xu.


Li Xu and Zhou Xinxia, the editing director and professor of Beijing Film Academy, discussed many times and decided not to adopt the conventional editing method of causal logic, but to try their best to show the richness of film language in the editing details. It took more than a year to finish the editing work.


Sunflower in the Evening took four years to complete, and it is planned to meet the national audience during the year. From the first shot, director Li Xu intended to immerse the audience in a quiet atmosphere. He hoped that after the release, everyone would take a break from the noisy real world, tidy up their mood, slowly walk into the illusory world where reality and unreality are intertwined in the film, and carefully feel the mental journey of a woman facing herself on the screen.


Hu Manzhi created and shared with you the "messenger" of intercellular communication-cytokines.

The future of cytokine detection is bound to be a red sea. You should know about these clinical applications.

Foreword:

In our bodies, there is a mysterious and powerful system, which always protects us from external pathogens. This system is our immune system, which is composed of many immune cells, like a well-trained army, always ready to resist foreign enemies. In this army, there is a mysterious force playing a role silently, which is cytokine.

Overview of cytokines

Cytokines are a kind of small molecular protein with wide biological activity, which is synthesized and secreted by immune cells (such as monocytes, macrophages, T cells, B cells, NK cells, etc.) and some non-immune cells (such as endothelial cells, epidermal cells, fibroblasts, etc.), and is equivalent to the "messenger" of mutual communication among various cells in human body.

It has many biological functions, such as regulating cell growth, differentiation and maturation, maintaining function, regulating immune response, participating in inflammatory reaction, wound healing and tumor growth and decline.

At present, the detection of cytokines is widely used in infections, kidney diseases, autoimmune diseases, tumors and malignant hematological diseases, which has important clinical significance in the diagnosis of diseases, the judgment of treatment opportunity, the guidance of medication, the monitoring of curative effect, the early warning of cytokine storm risk and the improvement of patients’ treatment efficiency.

Classification and main functions of cytokines

According to their main functions, cytokines can be divided into the following categories: interleukin (ILs), colony stimulating factor (CSFs), interferon (IFNs), tumor necrosis factor (TNFs), growth factor (GFs) and chemokine (CK).

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There are both pro-inflammatory factors and anti-inflammatory factors. Pro-inflammatory factors usually regulate the growth, activation, differentiation and homing of immune cells to infected sites, aiming at controlling and eradicating intracellular pathogens (including viruses); Anti-inflammatory cytokines are a series of immunomodulatory molecules that control the response of pro-inflammatory cytokines.

In the development of infection, the interaction between pro-inflammatory factors and anti-inflammatory factors runs through, which has a far-reaching impact on the development direction and outcome of infection.

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Clinical application value of cytokines

1, early diagnosis of infection, conducive to disease monitoring.

Shortening the window period helps to realize early diagnosis and win valuable time for treatment; The half-life is short, which is convenient to monitor the efficacy in time and ensure the effectiveness and safety of treatment; Complement with PCT and CRP, improve the accuracy of diagnosis and provide strong support for precise treatment.

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Note: In the Expert Consensus on Interpretation of Clinical Significance of Infection-related Biomarkers published in 2017, IL-6 has been regarded as one of the infection-related biomarkers.

2, help to determine the type of infection.

A study showed that IL-6 and IL-10 increased more than 10 times at the same time, suggesting G- bacteria infection; IL-6 increased by 2 times, and IL-10 increased by less than 10 times, suggesting G+ bacteria infection. According to the cytokine spectrum, the effective rate of identifying Gram bacteria to guide antibiotic treatment is close to that of broad-spectrum coverage group, up to 85%, while the effective rate of empirical treatment group is only 60%.

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3. Early warning of cytokine storm

During the period of COVID-19, many critically ill patients suffered from uncontrolled release of cytokines such as IL-6, IL-8, TNF-α, IFN-γ, which led to coagulation storm, thrombosis, myocardial infarction and pulmonary embolism, leading to respiratory failure, organ failure and even death.

Although IL-6 is the key cytokine for everyone at present, it should not be the only one. Cytokines is a huge regulatory network, which is coordinated with each other, constantly changing dynamically and changing with the course of disease.

Therefore, it is suggested that patients at risk of cytokine storm should be jointly tested for cytokines during admission and hospitalization.

4. Assess the inflammation and immune status of the body.

Severe patients may have three inflammatory/immune states: SIRS (Systemic Inflammatory Response Syndrome), CARS (Antagonistic Inflammatory Response Syndrome) and MARS (Mixed Antagonistic Response Syndrome).

When infection or other reasons lead to the imbalance of inflammatory response, if the levels of a large number of proinflammatory factors such as IL-1β, IL-6, IL-8, IL-12, IFN-γ, IFN-α and TNF-α are greatly increased, there is a risk of systemic inflammatory response syndrome -SIRS, and the inflammatory response of the body is strong at this time, so it is recommended to give priority to anti-inflammatory treatment; If the endogenous anti-inflammatory reaction is too strong, the anti-inflammatory factors such as IL-4 and IL-10 will be greatly increased, which indicates the risk of CARS. At this time, the immune function of the body is weak, and it is suggested to strengthen the immune treatment. If both pro-inflammatory factors and anti-inflammatory factors increase significantly, it suggests that the body is a mixed antagonistic response syndrome, suggesting that the body has a strong inflammatory response and low immune function, and it is suggested to carry out anti-inflammatory combined with immune enhancement therapy.

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5. Cytokines and Tumor

Cytokines are the key proteins of signal transmission in tumor microenvironment (TME), which have pleiotropic effects. In terms of anti-tumor, interferon and TGF-β can directly inhibit the growth of tumor cells, while IFN-γ, IL-2, IL-12 and IL-15 can enhance the cytotoxic activity of lymphocytes or bone marrow cells, thus inhibiting cell growth; In promoting tumor, TGF-β, TNF, IL-1β, CXCL12, etc. can promote the survival and proliferation of tumor cells; TNF, IL-6, etc. can cause the disorder of cytokine regulation and promote the occurrence of tumor inflammation; IL-10, IL-4, TGF-β, etc. are immunosuppressed; TNF, IL-6 and various chemokines can also promote angiogenesis.

Studies have confirmed that IL-6, IL-10 and IL-12 are slightly increased, while IL-2, TNF-α and IFN-γ are significantly decreased, suggesting that there may be early tumor microenvironment progress. Early warning of the occurrence of adverse reaction cytokine release syndrome (CRS) caused by PD-1 therapy /CAR-T therapy.

6. Cytokines and Autoimmunity

Hemophagocytic syndrome (HLH):HLH may be caused by persistent antigen stimulation caused by autoimmune diseases or malignant tumors, with high mortality. IL-2R is one of the diagnostic criteria (from China Expert Consensus on Diagnosis and Treatment of Hemophagocytic Syndrome). In addition, the slight increase of IFN-γ, IL-10 and IL-6 can also distinguish HLH from infection, which is helpful for the treatment of HLH patients.

Systemic lupus erythematosus (SLE): As a chronic autoimmune disease, SLE will affect many organ systems, including but not limited to skin, joints and kidneys. Cytokines in active SLE patients, including IL-8, IL-18, IL-6 and IFN-α, were significantly higher than those in inactive SLE patients. Especially, IL-6 and IL-8 showed better sensitivity and specificity than traditional C3, C4 and Anti-dsDNA.

Henoch-Schonlein Purpura (HSP): A large number of studies show that inflammatory cytokines in HSP patients are out of balance, mainly IL-6, IL-8 and TNF-α. When the cutoff value of IL-6 is set to 7 pg/mL, the sensitivity and specificity can reach 78.0% and 80.5%. The change of IL-8 will be greater, which is 2-10 times of the baseline level of healthy people.

7, cytokines and asthma, allergic diseases and lung diseases.

Generally speaking, children’s allergic diseases such as asthma and allergic rhinitis are mainly mediated by humoral immunity (IgE-mediated type I allergy). IL-4 and IL-5 can promote the secretion of IgE antibodies, aggravate allergic diseases, monitor the levels of IL-4 and other proinflammatory factors, and evaluate the condition and efficacy.

In addition, pro-inflammatory cytokines such as IL-6, IL-8 and TNF-α can promote the progress of airway inflammation such as chronic obstructive pulmonary disease (COPD) and pneumonia, and evaluate the changes of cytokine levels, so as to evaluate the disease progress and drug efficacy monitoring of the above diseases.

8. Cytokines and Reproductive Medicine

Studies have proved that Th1 cytokines are significantly increased and Th2 cytokines are decreased in patients with unexplained recurrent abortion. It has also been reported in the literature that the significant increase of IL-22 concentration may be related to unexplained recurrent abortion.

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Advantages and disadvantages of mainstream detection methods for cytokine reagents

1, chemiluminescence method

Advantages: The method is mature and stable in technology, high in sensitivity and wide in linear range, and can efficiently complete single detection in a short time.

Disadvantages: it is impossible to carry out multi-project joint inspection and the sample demand is large, which makes it unable to cope with the large sample size test.

2. Flow fluorescence method

Advantages: As a relatively new detection method, flow fluorescence method stands out for its advantages of realizing multi-item joint inspection with small sample size, especially in large sample size testing, which saves time and cost.

Disadvantages: It may not be as sensitive as the light-emitting platform, and it is difficult to solve the interference problem that may be introduced in the process of multi-joint inspection, which affects the accuracy of its detection to some extent.

3. Enzyme-linked immunosorbent assay

Advantages: The method is mature and stable, with high sensitivity and good stability.

Disadvantages: the reaction time is relatively long, the linear range is narrow, and the detection efficiency is low, so it is more used in scientific research.

Market situation and current situation sharing of cytokine reagents

1. The domestic heat is higher than that of foreign countries.

Through investigation, we found that, for cytokine projects, except IL-6, foreign manufacturers are more respected, and almost no other manufacturers have obtained certificates in China or even CE. At present, only Siemens has obtained the registration certificates for six projects, namely IL-1β, IL-2R, IL-6, IL-8, IL-10 and TNF-α, in China, which is regarded as an early cytokine project company that entered the China market.

The joint inspection of cytokine combination project seems to be a unique project in China, and it is difficult for us to find similar packaged tests in other countries.

From the actual clinical point of view, COVID-19 and sepsis have confirmed the significance of IL-6 detection, and hemophagocytic syndrome has clarified the value of IL-2R detection. However, for other cytokine detection, although everyone is advocating the clinical significance of each index, there is no more recognized expert consensus to explain it. It can only be said that the market prospect is there, but more clinical practice is needed to confirm it.

At present, there are mainly two factions in the detection of cytokines in China, such as the magnetic particle light-emitting platform of Hot Scene Bio, which has obtained the registration certificates of 13 indicators, namely TNF-α, IFN-γ, IL-1β, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-8, IL-10 and IL. At present, the flow fluorescence platform made by Hu Manzhi is generally combined with 12 items, namely TNF-α, IFN-α, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12p70 and IL-11.

2. Although there are international standards for each project, the testing situation of each manufacturer is not uniform.

Due to the lack of foreign reagents, it seems difficult to maintain the consistency of test results except IL-6. Although almost every project has international standards, from the data of clinical tests, the test results of various manufacturers deviate seriously, and it is difficult to judge which manufacturer’s test value is more accurate. It may be inferred that the traceability chain of each manufacturer is not particularly strict.

We know that most cytokines can’t be stored stably at room temperature, so the general calibrators are in the form of freeze-drying, which may be due to the loss during freeze-drying, or the interference of composite quality control such as flow platform, or the matrix effect introduced in the dilution process of international standards, which makes the test results of reagents difficult to be unified and leads to confusion in clinical judgment.

Market prospect of cytokine detection reagents

Although we have mentioned the problem that various cytokines form a complex network of communication and restriction between cells, there is no disease-specific guidance for many indicators at present, and it is difficult to unify the test results among manufacturers, but on the other hand, it is a huge opportunity for reagent manufacturers. Why do you say that?

First of all, the broad indications of detection indicators mean that cytokine items can be detected in various departments, with a large volume; Moreover, there are not many manufacturers in this testing field, and compared with conventional testing items, the homogenization is not serious and the market prospect is relatively broad; Moreover, the difference in the test results of manufacturers will inevitably lead to the emergence of benchmark enterprises in this field, so many enterprises can establish their own brand image through this product; It is believed that with the further implementation of the consensus of experts in various fields and the gradual maturity of emerging technologies such as flow fluorescence and single molecule detection, cytokine detection will surely be a red sea.

Today’s sharing is here, I hope it will inspire you. (For more information about cytokine detection reagents, please search the official website of HUMAN Zhizhi and click to inquire.)

About Hu manzhizao

Beijing Human Zhizao Technology Co., Ltd. is a medical technology innovation company integrating R&D, production and sales. With years of experience in materials science, in vitro diagnosis technology and marketing, based on the core of multi-flow fluorescence technology, the company is committed to providing fully automatic multi-flow fluorescence detection platform and supporting reagents with competitive advantages for clinical customers, and has built a "new ecology" for ultra-high-speed immunodiagnosis, focusing on major immune diseases, intractable diseases and rare diseases.

Heavy! The tenth edition of COVID-19 diagnosis and treatment plan adjustment points.

  Recently, the National Health and Wellness Commission and state administration of traditional chinese medicine organized the revision of the novel coronavirus Diagnosis and Treatment Plan (Trial Ninth Edition) and formed the novel coronavirus Infection Diagnosis and Treatment Plan (Trial Tenth Edition). The key revisions are as follows:

  The name of the disease has been adjusted.

  According to the "Overall Plan for Implementing" Class B and B Management "for novel coronavirus Infection by the Comprehensive Group of the State Council Joint Prevention and Control Mechanism, the name of the disease was changed from" novel coronavirus "Renamed "novel coronavirus Infection". With the continuous variation of Covid-19, the virulence of Omicron virus weakened after it became the main epidemic strain. The main symptoms of human infection were cough, fever, sore throat and so on, and only a few infected people would progress to pneumonia.

  No longer judge "suspected cases"

  With the increasing richness of diagnostic methods and the continuous improvement of diagnostic efficiency,At present, Covid-19 infection can be diagnosed promptly, quickly and accurately by nucleic acid and antigen detection.In most cases, there will be no cases where the epidemiological history and clinical manifestations are consistent with the characteristics of the disease, but the pathogen detection can not be clear for a long time.

  Increase the positive test of Covid-19 antigen as diagnostic criteria.

  Antigen detection has good detection sensitivity for infected people with high viral load.With the maturity of antigen detection technology and the improvement of detection accuracy, Covid-19 infected people, especially those with strong infectivity, can be diagnosed in time through antigen detection.Considering that most infected people are treated at home, the antigen detection operation is simple and convenient, which is convenient for infected people to carry out rapid self-detection.

  Further optimize "clinical typing"

  With the constant variation of the virus, especially since the epidemic of Omicron strain, the pathogenicity of the virus has been gradually weakened, and the characteristics of the disease have changed obviously. Most infected people have mild symptoms and the proportion of pneumonia has been greatly reduced.In order to better reflect the characteristics of the disease, the tenth edition of the plan adjusted the clinical classification, mainly according to the severity of the infected person’s illness, divided into "light, medium, heavy and critical", which is more in line with clinical practice.

  Cases are no longer required to be "centralized and isolated"

  With the implementation of Class B and B management measures, Covid-19 infected people can choose home treatment or medical institutions according to the needs of treatment, and all kinds of medical institutions can treat Covid-19 infected people.

  Further improved the treatment method.

  The anti-Covid-19 drugs that have been approved for marketing in China will be included in the new diagnosis and treatment plan to further enrich the antiviral treatment methods.

  Further improve the diagnostic criteria and early warning indicators for severe and critical cases, and scientifically and accurately judge severe cases of infection in Covid-19. At the same time,The elderly who have not been vaccinated in the whole process will be added to the high-risk group of severe diseases, and the monitoring of vital signs, especially the monitoring index of finger oxygen saturation after rest and activity, will be added to the early warning index of severe diseases..

  Further strengthening the concept of co-treatment of Covid-19’s infection and basic diseases, emphasizing the need to strengthen the monitoring of related indicators of infected people’s basic diseases and give corresponding treatment for basic diseases, which is more conducive to promoting patients’ comprehensive recovery.

  Further optimize the clinical manifestations and treatment-related contents of children’s cases, put forward the characteristics of children infected with Omicron strain in combination with clinical practice, and improved the early warning indicators of severe cases in children.It provides a treatment plan for special situations such as acute laryngitis and nervous system complications that may occur in children infected.

  Further improved the related content of Chinese medicine treatment.Strengthen the guidance of traditional Chinese medicine treatment for severe and critical cases, and increase the method of medication with symptoms, which is more suitable for clinical practice.On this basis, the Chinese medicine treatment plan for children’s cases is further improved, acupuncture treatment methods are added, and corresponding Chinese medicine treatment measures are provided in combination with the obvious cough of some patients in recovery period.

  Adjust the "discharge standard"

  The tenth version of the plan no longer requires the results of nucleic acid detection when the infected person leaves the hospital, but the clinician makes a comprehensive judgment based on the patient’s Covid-19 infection, diagnosis and treatment of basic diseases or other diseases, and health recovery.

  When the patient’s condition is obviously improved, his vital signs are stable, his body temperature is normal for more than 24 hours, lung imaging shows that acute exudative lesions are obviously improved, and he can be converted to oral medication, and there are no complications that need further treatment, he can consider leaving the hospital.

  Adjust the prevention and control of infection in medical institutions

  After the adjustment of the epidemic prevention and control policy, all medical institutions have the possibility to accept cases of Covid-19 infection. The tenth edition of the diagnosis and treatment plan has adjusted the relevant contents of infection prevention and control in medical institutions.

  Further implement the system of pre-examination and triage for outpatient and emergency departments and do a good job of patient diversion. At the same time, instruct patients and accompanying personnel to wear medical surgical masks or medical protective masks, and provide instructions on hand hygiene, respiratory hygiene and cough etiquette.

  Strengthen the cleaning, disinfection and ventilation of consultation rooms, wards, offices and duty rooms.

  Implement personal protection requirements of medical staff according to exposure risks.

  Standardize the treatment of medical waste and implement terminal disinfection after patients are transferred out or discharged from hospital.

  ▌ This article Source: CCTV News WeChat WeChat official account (ID: CCTV News Center)

  Producer/Editor-in-Chief Bing Xu/Ma Wenjia

  Headquarters reporter/Shi Yingchun

  Editor/Yu Zijing Drawing/Gao Mengru

  Image source/vision china

Five practical skills of Huawei Pura70 are shared, and new users should try it quickly.

Huawei Pura70 series has been released for many days, and I believe many small partners have already touched it.

I’ve seen a lot of introductions of new functions and new hardware these days. I wonder if you pay attention to the changes in experience. Huawei Pura70 series is equipped with the latest HarmonyOS 4.2, and there are still many changes in details. For many new users, if you don’t study it in depth, you may regret missing it. Then take stock of a few more interesting functions, take a new machine in hand, or plan to start a new machine, you can take a look.

1. "Shake" to intercept jump advertisements

I don’t know which product manager invented the "shake" jump advertisement, but I guess his performance must be very good.

In any case, it is necessary for the mobile phone to stop the "shake" advertisement. After all, it is really useful.

I am deeply touched by this point. During the Double Eleven last year, I still used it. It didn’t have the advertisement interception function. As a result, some apps were opened at one point, and the first thing I jumped to was the shopping platform, which was annoying. It was changed at the beginning of the year. Starting from the latest surge, this mobile phone supports "getting device movements and directions" on and off, and the experience has also been qualitatively improved.

With the release of Huawei Pura70 series, Huawei users can also set the "Application acquisition device direction" for the app in this mobile phone. Personally, this function is not bad, and new users can turn it on or off as needed. Of course, if it is set to prohibit, in addition to shaking the advertisement jump, the game control and automatic screen flipping may also be affected, which needs attention.

2, photo AI elimination

With the explosion of the concept of "AI big model", some useful AIGC functions have been widely used, such as image elimination.

At present, mainstream flagship mobile phones such as Huawei, Glory, OPPO, vivo and Xiaomi all support the AI ? ? picture elimination function, and their performance is naturally mixed.

The image elimination function of Huawei Pura70 series is good in some scenes, and the overall evaluation can be given to the upper-middle. I believe it will be better with the optimization of subsequent systems and the improvement of large model capabilities.

3. Smart screen recognition

Smart screen recognition is a super easy-to-use function, but 99% of consumers actually don’t care.

For example, if you want to recognize the words on the picture, cut out some words, logos or photos, or translate between Chinese and English, compare prices of goods, etc., in the past, you needed a three-party App, or manually search for some more complicated menu operations. If you use smart screen to operate, it will be very convenient and fast.

On Huawei Pura70 series, users only need to hold down the screen with two fingers at the same time, which can trigger the intelligent screen recognition function, which can be carried out in any interface, including the operation of coding chat records with one button.

4. Artistic protagonist

The artistic protagonist is a custom theme function, and users can set their own photos as themes. The difference is that this function supports powerful customization. When you set a photo, the system will automatically matting the portrait, and users can also adjust the image at will.

In addition, the artistic protagonist has a wealth of texture styles and colors to choose from to meet the personalized needs.

5. Interactive theme

It also belongs to the category of theme customization. Unlike traditional static themes or dynamic themes, Huawei Pura70 series provides several themes that can interact with users. In addition to supporting sticker customization, it can also interact with users. For example, when users light up the screen, the wallpaper will move, and when the screen is turned off, the wallpaper will also move; Every time you slide into the desktop, the sticker will show a different animation form. Even when you click on the sticker with your finger, it will respond accordingly, which not only fills up the visual effect, but also makes every operation more interesting.

That’s all about the sharing of new functions of Huawei Pura70 series. Don’t forget to give it a try for new users. They are all very interesting and practical functions, which I believe will bring you a different experience.

Don’t buy the "back from the dead" flowers that are screened by friends!

  Cctv newsRecently, in the circle of friends and the homepages of various social media, many people are drying a flower that can bring life back to life.

  A dead branch without roots.

  Soak it in water for a few days and it will bloom again.

  This kind of dry branch is called "Rhododendron in Daxinganling"

  Is it really that amazing?

  The flowers that came back to life in the circle of friends were warned to destroy the ecological environment.

  The WeChat circle of friends of Ms. Liu, a native of Hangzhou, was screened by this magical "dead wood in spring": "Many people are taking pictures. I also bought one to 20 yuan, which is much cheaper than the flowers in the flower shop. "

  After receiving the dead branch, Ms. Liu put it in the water. In less than two weeks, the branch bloomed with pink and purple flowers, which had a literary beauty. In another week, the flowers have fallen, and young leaves are beginning to come out from the branches, which is a different scenery.

  She exposed this moment of witnessing "miracle" to a circle of friends, but received a dissuasion message from a friend: "Don’t buy this again! This dead branch is broken from wild rhododendron, which will destroy the ecological environment! "

  She is not the only one who received dissuasion messages in the circle of friends. Weibo netizen "Xicheng Green" also said that he was told not to buy this kind of flowers after drying them in a circle of friends.

  Is this true or not? Will it really damage the environment to buy azaleas and raise them at home?

  A bunch of online shops in 20 yuan sell wild rhododendrons.

  The reporter browsed a shopping website, and the pictures below the keywords "Rhododendron hydroponics, dry branches, soaked flowers, dry wood and dead trees meet spring flowers" are all Rhododendron flowers in Xing ‘an, and the store specially added the words "artificial cultivation" and "home planting". Only a few stores still write "dry branches of rhododendron in Xing ‘an" in the product description.

  But the commodity maps are all similar, with pink and purple flowers on the dead branches. People who know a little about flowers can recognize this as azaleas at a glance.

  According to the commodity details of these azaleas, dead branches can bloom in about 7-10 days after being inserted in water and changed once every 3-4 days. If you don’t want it to open for a while, just put the dead branches in the refrigerator for preservation.

  Some stores focus on "wild", and in the product details, they have exposed many photos of flowers and trees in the snowy mountains, as if to prove to buyers that these branches were indeed picked from the mountains.

  According to the customer service of an online shop, these dead branches were imported from the local flower and bird market. People in the market told them that it was wild in the mountains of Daxinganling. As for whether it was true or not, the seller was not sure himself.

  Among these shops selling dead branches, the one with the highest sales volume sells 7,787 orders a month, and the price is 40 sticks in a bunch of 23 yuan. The more you buy, the lower the unit price. In this way, the number of dead branches to be sold every month is not a small number.

  Flowers can bring back the dead? It’s not that amazing!

  Why do dead branches that look lifeless bloom quickly when inserted in water? Experts say that these dead branches are actually not dead at all, just "hibernating"!

  This kind of rhododendron, which grows in Daxing ‘anling and Xiaoxing ‘anling areas, is scientifically called Rhododendron Xing ‘an, also known as Tartar Fragrant, and is the city flower of Yichun City, Heilongjiang Province. It belongs to semi-green shrub, leaves fall and sleep in winter, waiting for the next spring to bloom again. In the dormant period, the branches are broken down, inserted into the water, and then placed in a warm room. The temperature and moisture have reached the conditions for flowering, and the buds on the dead branches naturally bloom.

  This "magical" process can be done not only by cuckoo, but also by branches such as peach blossom and winter jasmine. Therefore, the so-called "coming back to life" is not a "miracle", but just a gimmick of the merchants.

  Expert: wanton logging will destroy the ecological balance.

  However, because of the "magic" stunt, Rhododendron Xing ‘an has been cut down a lot.

  In fact, in 2017, Huzhong District, Daxing ‘anling, Heilongjiang Province issued the Notice on Prohibiting the Collection and Sale of Rhododendron Xing ‘an, because the growth of wild Rhododendron Xing ‘an is slow, only 10 cm long a year, and the rampant deforestation has seriously affected the ecological environment.

   According to experts, the natural environment is a house with balanced distribution. If a large number of azaleas are cut, its ability to absorb sunlight and water will be weakened. This energy will be taken up by other plants, and the cuckoo will only become weaker and weaker.

  In addition, as a woody plant, Rhododendron itself grows slowly, and it takes 5-6 years from sowing to first flowering; If it grows into a branch that can be broken by dozens of centimeters, it is at least twenty or thirty years old. If you want to make it grow back, it will not be so fast.

  Appeal: Don’t pick and buy wild plants.

  Although the local government has taken measures, rhododendrons in Xing ‘an will still be cut and sold in winter.

  Beauty should not be at the expense of injury. I appeal to everyone: don’t buy rhododendron in Xing ‘an, and don’t pick wild plants at will. Let these plants live in their original homes!

  Source: Sichuan Daily WeChat WeChat official account

China FAW Yancheng Branch put into production, the first model Pentium pony was officially mass-produced.

On May 17th, China FAW Yancheng Branch was put into production and the first car mass production ceremony was officially held. Pentium pony, the first model born in the new factory, was mass-produced and shipped to its dealers all over the country. With the mass production of the first car, the new energy factory of China FAW Yancheng Branch was officially unveiled for the first time, which opened the Pentium brand of China FAW and accelerated the development of new energy industry layout.

Relevant responsible persons from Yancheng Municipal Party Committee and Municipal Government, China FAW, FAW Pentium, Yancheng Economic and Technological Development Zone and Jiangsu yueda Group came to the scene to witness this important moment. The main responsible comrades of Yancheng Municipal Party Committee and Municipal Government, Wang Guoqiang, director and deputy secretary of the Party Committee of China FAW Group Co., Ltd., Yang Chang, chairman and secretary of the Party Committee of FAW Pentium Automobile Co., Ltd., and Kong Dejun, general manager and deputy secretary of the Party Committee of FAW Pentium Automobile Co., Ltd. jointly launched the commissioning and first car mass production ceremony of China FAW Yancheng Branch.

Wang Guoqiang said in his speech that as an important part of the strategic layout of China FAW’s new energy industrial chain, the commissioning of China FAW Yancheng Base greatly supplemented the production capacity layout of China FAW’s independent new energy vehicles, marking a key step in the strategic layout of China FAW’s new energy. As the first new energy strategic model of Pentium brand, Pentium Pony will further enhance the competitiveness and influence of Pentium in the new energy market, and bring more scene and personalized car experience to consumers.

As a new energy passenger car production base established by China FAW, Yancheng Branch will undertake the production tasks of various new energy main models of Pentium brand in the future, which will become an important guarantee to support the development of China FAW’s own brand and promote the transformation of FAW Pentium’s new energy. With the accelerated transformation, FAW Pentium will launch seven new energy vehicles, covering pure electric, plug-in hybrid, extended range power and other types of products.

Pentium pony is the first product of FAW Pentium’s new energy transformation, which will be officially launched on May 28th. Since the pre-sale, it has become the new "budding master" of the micro pure electric travel market with the five good experiences of "good-looking, fun, easy to open, economical and safe".

In addition, the brand-new new energy vehicle of Pentium brand, code-named E311, also made its debut at the event. This vehicle is an all-electric SUV with high price-performance ratio and high quality-price ratio, which will bring consumers a brand-new travel experience with cutting-edge technology.

The commissioning of China FAW Yancheng Branch will bring sufficient capacity support and quality assurance for the planning and landing of new energy products of FAW Pentium. By the end of this year, China FAW Yancheng Branch will invest and transform 30 production lines one after another, reaching the annual output of 100,000 vehicles, and the production capacity will exceed 150,000 vehicles by the end of 2025, making it an intelligent, green and efficient modern manufacturing enterprise. In terms of manufacturing quality, it can realize 100% automation, high precision and zero error in body welding, and 100% data upload in final assembly can realize traceability of vehicle quality. In terms of quality inspection, the laser radar with a measurement accuracy finer than the hair ensures the uniform and beautiful gap between vehicles, and the detection intensity of rain around 360 degrees reaches more than twice the national standard. Through more than 16 kinds of complex road conditions tests, 19 rigorous tests in 4 categories are carried out in the whole process, which reflects the quality standards of China FAW.

From the official mass production of Pentium pony to the surprise appearance of E311, and then to the high standard landing of Yancheng New Energy Factory, FAW Pentium has entered a new round of strategic transformation. Relying on more than 70 years’ accumulation of China FAW and Yancheng’s complete industrial supporting facilities, FAW Pentium will reinforce its advantages in the Yangtze River Delta market, which is the core of new energy vehicle consumption, showing a new pattern of coordinated layout of North-South bases and common development of North-South markets.

Be alert! These bacteria may cause diseases such as sepsis and meningitis.

  In summer, the weather is hot, and the growth and reproduction of bacteria are increasingly active. The so-called "illness from the mouth", when cooking dishes, do you think that there may be "dangerous elements" hidden in the kitchen? What diseases will they cause?

  What are the common pathogens in the kitchen?

  1. Escherichia coli

  ● Can cause diseases: sepsis, infective endocarditis, liver abscess, peritonitis, pelvic inflammatory disease and urinary system infection.

  ● Symptoms after infection: abdominal pain, diarrhea, fever, nausea, dizziness, vomiting and shock.

  E. coli is harmless to human body under normal circumstances, but it is easy to cause disease once it is overdosed and human immunity is weak.

  ● E.coli has low requirements for living conditions, and it will grow in the kitchen where there is a little water or food residue, such as chopping boards, rags and sinks that have not been dried. It is warm and humid in summer, and the growth and reproduction of Escherichia coli is very fast.

  ● Escherichia coli is not resistant to high temperature. Generally, it can be killed in plain areas by boiling at 100℃ for about 15 minutes to 30 minutes. When the temperature is about 4℃, the growth rate of Escherichia coli slows down; When the temperature is below MINUS 20℃, it enters a dormant state and stops breeding.

  2. Listeria

  ● Can cause diseases: fetal arrest, abortion, meningitis.

  ● Symptoms after infection: abdominal pain, diarrhea, fever, nausea, dizziness, vomiting and shock.

  Listeria is known as the "refrigerator killer" and can still grow at 4℃. Milk, yogurt, eggs, meat, cold drinks and vegetables in the refrigerator may be parasitic.

  Low high temperature environment is easy to kill Listeria, and refrigerated food can be sterilized by boiling and heating. In addition, regular cleaning and disinfection of the refrigerator will help to eliminate Listeria.

  3. Vibrio parahaemolyticus

  ● Can cause diseases: gastroenteritis, acute renal failure and wound infection.

  ● Post-infection symptoms: severe abdominal pain, diarrhea, fever, nausea, dizziness, vomiting and shock may occur.

  ● Vibrio parahaemolyticus mainly lives in seafood such as fish, shrimp, crab, shellfish and seaweed. Eating food containing this bacterium or being scratched by food containing this bacterium can cause infection.

  ● Vibrio parahaemolyticus can be killed by heating at high temperature. If sterilized with boiling water, it is recommended to boil for more than 15 minutes.

  4. Salmonella

  ● Can cause diseases: bacteremia, septicemia, gastroenteritis, osteomyelitis, meningitis, vascular implant infection and bone and joint infection.

  ● Post-infection symptoms: persistent high fever, abdominal pain, diarrhea, nausea, dizziness, vomiting and shock may occur.

  Salmonella is easy to appear in kitchen knives, chopping boards, vegetables, fruits, eggs, chicken legs and other foods.

  Salmonella can be killed by heating at high temperature.

  5. Staphylococcus aureus

  ● Can cause diseases: meningitis, otitis media, septicemia, pneumonia, folliculitis, wound infection and paronychia.

  ● Post-infection symptoms: skin pustules, abdominal pain, diarrhea, fever, vomiting, dizziness, etc.

  ● It is often parasitic on human and animal skin, nasal cavity, throat, stomach and other tissues, and is also found in air and sewage. When eating food contaminated by the bacteria, or when the body wound comes into contact with pollution sources, it can cause infection.

  Staphylococcus aureus has a certain tolerance to high temperature, and it can be killed in a high temperature environment above 80℃ for 30 minutes. 70% ethanol can also be used for disinfection.

  The doctor reminded that the symptoms caused by these pathogenic bacteria when invading the human body have many similarities, such as diarrhea, abdominal pain, fever, etc. Therefore, once an infection occurs, it is necessary to go to the hospital for examination and test to accurately identify which kind of bacteria is caused, and then take medicine for the symptoms.

  Transferred from CCTV Finance

[Editor in charge:

]

Baojun responded to Yue brake failure, and software BUG caused brake degradation.

Recently, some car owners posted on social platforms that the brakes of the 2023 smart driving version were abnormal, which attracted the attention of netizens.

On January 4th, Baojun Automobile issued a statement in the official Weibo to respond to the relevant situation. The statement said: "This Yueye incident is not the’ brake failure’ described by the network, but the existence of some vehicles.Software BUG, resulting in the brake assist degradation. This part of the vehicle will enter the speed limit protection state when it is reminded by the indicator light when it is started. "

"After receiving relevant feedback, we intervened in the first time and solved the user’s vehicle problem. Please feel free to use it." Baojun Automobile said, "Without knowing the facts, the relevant media described the words such as’ brake failure’ as inaccurate."

Previously, many car owners reported on social media that the brakes of Baojun Yueye had failed, mainly focusing on the 2023 Baojun Yueye Flagship Edition and Zhizun Edition. The vehicle reported eps code, and the "yellow turtle" fault light appeared on the dashboard. The owner stepped down.brake pedalThe rear vehicle cannot slow down.

A car owner described the problem as follows: "When I was driving on the morning of December 31, 2024, I found that the car slipped after the car was powered on, and there was no response when I stepped on the brakes. I started the car several times without power, and the problem still existed. At the same time, the vehicle dashboard reported the EBS fault light and the drive system fault light, so I called for rescue and dragged the car to the 4s shop for maintenance. So far, the cause of the vehicle problem and the after-sales plan have not been clearly answered."

Stephy’s American-born daughter came back to take a selfie, showing good looks and recovering quickly.

Stephy takes selfies.

Weibo screenshot

    1905 movie network news Recently, Stephy Nathan Scott Lee showed up at Beijing Capital Airport with his daughter, which proved that the whole family had returned to Beijing. At 19: 31 on April 8th, Stephy Weibo took a selfie. In the photo, Stephy took a selfie with a camera in one hand and made an "OK" gesture in the other. Different from the past, the neat short hair has turned into a long hair, which is more charming, and the skin is white and smooth. Postpartum recovery can be called rapid.

    After the exposure of this Weibo, netizens sent blessings one after another, and some netizens ridiculed: "Does this gesture mean a baby brain for three years?"

??

    It is reported that in August 2013, Stephy and American Han Xing Nathan Scott Lee were photographed by the media returning to the apartment together after a barbecue in the middle of the night, and their love affair was open. On August 25th, 2014, Stephy officially announced the wedding news through Weibo, and took a photo with her fiance Nathan Scott Lee. On September 8th, Stephy and Nathan Scott Lee formally married at Caesar Palace Hotel in Las Vegas, USA. On January 17th, 2015, Stephy had a baby girl in Hoag Beach, California. She was nicknamed "Lucky" and weighed 3145g at birth.

Some lesions in the annual physical examination can’t be found? Expert: Physical examination needs a "sense of design"

  Medical Guidance/Professor Wang Fangjun from the First Affiliated Hospital of Guangzhou University of Chinese Medicine

  No matter on the Internet or in real life, I can always hear people asking similar questions angrily and helplessly: one of my relatives and friends has a physical examination every year, and no problems have been found. Who knows that lung cancer has been found recently, or it is in the advanced stage! Therefore, people often ask bluntly: What is the use of physical examination? Why are some diseases still undetected? The reporter interviewed Professor Wang Fangjun from the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine.

  Text, Figure/Guangzhou Daily All-Media Reporter Weng Shuxian Correspondent Fang Ning and Zhang Qiuxia

  Don’t wait for the body to "hold on" before doing the examination.

  "Physical examination is of course useful! The use is not small! " Wang Fangjun explained that the so-called physical examination is the abbreviation of "physical examination", which is a process in which doctors use their own senses, auxiliary examination instruments and experimental equipment to collect objective information on the health of patients or normal people and conduct health assessment.

  In the past, many people went to the hospital after they felt obvious symptoms of the disease, or even "unbearable". As everyone knows, many diseases have no discomfort in the early or even the middle stage, especially cancer. When the symptoms are obvious, they often have developed to a serious stage, and the treatment effect is difficult to guarantee, even for life. Physical examination is a process in which people take the initiative to evaluate the health status of their bodies. Without waiting for the body to send out an obvious "unbearable" signal, they can find hidden dangers of diseases as early as possible and block the progress of diseases in time.

  Why didn’t the physical examination find early lesions?

  Why do you insist on physical examination every year, or are some early lesions not found in time? What do you think about this problem that puzzles many people?

  "We should be clear about the fact that the health examination of normal people is not the same as the disease examination of patients who go to the hospital to see a doctor!" Wang Fangjun said that the examination of diseases is clear-cut, targeted, accurate and meticulous, and will make a relatively accurate diagnosis of diseases in a "positioning, quantitative, qualitative and regular" manner; The physical examination is only a screening process, and we don’t know whether the body is sick or not, which is equivalent to "casting a net". Therefore, we usually only choose some simple and cheap items that can reflect important organ functions.

  If we sort out these "casting a net" health examination items, he thinks they can be roughly divided into three categories:

  1. General examination: It belongs to the most basic examination items, and usually includes blood pressure measurement, heart and lung examination, electrocardiogram examination, palpation of liver, gallbladder, spleen and lymph nodes, etc., so as to roughly judge whether there are diseases of organs such as hypertension, heart disease, lung disease and liver and gallbladder.

  2. Laboratory examination: generally including blood analysis (blood routine), urine routine, liver and kidney function, blood lipid analysis, tumor markers and thyroid function, to judge whether there are anemia, infection, hepatitis, nephritis, hyperlipidemia, tumor, leukemia and hyperthyroidism.

  3. Imaging examination: it is essential in the current physical examination, which usually includes chest X-ray photos, B-ultrasound (liver, gallbladder, spleen, kidney, thyroid, etc.) and other items.

  "Whether you apply for a medical examination on your own initiative or a medical examination organized by your work unit, you only choose a few inspection items to do." Wang Fangjun said that even "people who are not poor in money" have designed an expensive "luxury medical examination package" according to their own requirements, and in fact it is impossible to include all kinds of examination items in the hospital. Therefore, in theory, it is impossible for physical examination to "exhaust all items", and there will always be some early lesions that will be missed. Some people only check a few small items, and they are not necessarily targeted. Therefore, some early lesions have failed to be detected.

  Tips: Optimize physical examination items to improve inspection efficiency.

  So, how to improve the effect of physical examination more pertinently?

  "In fact, the physical examination is also ‘ Technical work ’ , also need to have ‘ Sense of design ’ 。” Wang Fangjun analyzed that the above-mentioned physical examination items can be regarded as the preferred basic items, and it is recommended that all the subjects can be seriously examined. In addition, some targeted projects should be optimized according to the characteristics of age, gender and occupation, so as to improve the inspection efficiency. And how to choose the best, it is suggested that we can communicate with the doctor appropriately and design the best physical examination plan with the help of the doctor.

  For example, he said that people over the age of 40 should appropriately increase items such as bladder, prostate, uterus and accessories when doing basic B-ultrasound (liver, gallbladder, spleen, kidney, thyroid, etc.) during physical examination; Women at risk of breast cancer should increase mammography and breast ultrasound; People at risk of heart disease can add items such as cardiac color Doppler ultrasound on the basis of ECG. If you are an older "smoker" or a patient with other high-risk factors of lung cancer, you should "upgrade" the chest X-ray photos to a low-dose CT examination of the chest to avoid missing the diagnosis of early lung cancer.

  If some parts of the body are obviously uncomfortable, that is to say, some symptoms or signs have appeared, then the goal of the examination is more clear. Wang Fangjun reminded that the physical examination at this time may wish to refer to the contents of "disease examination" and ask the specialist to "tailor-made" the examination items, so as not to miss the early or even middle and late lesions.

  Related links

  The free physical examination at home is coming!

  Online booking service is open now.

  Guangzhou Daily News (all-media reporter Wu Shen) Is your figure healthy or invisible obesity? How about cardiopulmonary endurance, physical flexibility and balance ability? If you want to know more about your body shape, function and quality, you should pay attention to this free welfare! Guangzhou Daily’s all-media reporter learned from Guangzhou Sports Science Research Institute that from today, residents of all districts in Guangzhou can make an APPointment to receive free physical fitness tests at national physical fitness monitoring sites all over 11 districts through the mobile phone app "Grouplink", and get a deep understanding of their physical function and physical quality through the tests of 11 projects, and get a personalized "exercise prescription".

  "I have a physical examination every year. Is there any difference in this physical examination?" The importance of routine physical examination has been popular, but physical fitness test is still a new thing for most people. Experts explained that the annual routine physical examination is to check whether there is any disease in the body, and all kinds of diseases and abnormalities can be detected; The purpose of physical fitness test is to fully understand the physical condition, and to find problems at the "sub-health" stage when physical function and physical quality begin to decline, so as to prevent the occurrence of diseases.

  For people who want to lose fat and gain muscle through exercise, for example, people who want to get rid of mild fatty liver through exercise can have a physical fitness test every three months to observe the exercise effect and adjust the exercise plan in time. For the general population who usually have good exercise habits, it is also necessary to have a physical fitness test every six months to one year.

  The National Physical Fitness Monitoring Center under the Guangzhou Sports Science Research Institute conducts physical fitness monitoring for specific people every year. In order to help the public fully understand their physical condition, prevent the occurrence of diseases, provide the residents with the basis for scientific sports and improve their physical and mental health, from September 20, the function of making an APPointment for physical fitness test will be launched on the "Qunshitong" app. Residents aged 19-69 can choose the nearest national physical fitness testing site and have a free physical fitness test within the scheduled time. Through 11 items such as body composition test, bone density test, step test, vital capacity test and grip strength test, you can get comprehensive evaluation electronic report and personalized exercise suggestion, which is a good opportunity to deeply understand your body shape, body function and physical quality.